Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9H081 / MIS12_HUMAN
Protein Name Protein MIS12 homolog
Gene Name Name: MIS12
Organism Homo sapiens (Human)

DAG View
PRO Name protein MIS12 homolog (human)
Definition A protein MIS12 that is encoded in the genome of human.
Short Label hMIS12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9H081 (MIS12) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S56 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q96BT3 (CENPT) S201 Q9H081 (MIS12) unknown eFIP 28012276
Phosphorylation Q9Y2Z0 (SUGT1) S331 Q9H081 (MIS12) increased_association eFIP 22869522

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K146 E146 Biomuta DOID:1324 / lung cancer [ cosmic ]