iPTMnet Report for Q9BQ70 (TCF25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQ70 / TCF25_HUMAN
Protein Name Transcription factor 25
Gene Name Name: TCF25
Synonyms:KIAA1049,NULP1;ORFNames:FKSG26;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQ70
DAG View
PRO Name transcription factor 25 (human)
Definition A transcription factor 25 that is encoded in the genome of human.
Short Label hTCF25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQ70 (TCF25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
R29 Methylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S81 Phosphorylation HPRD   PhosphoSitePlus 20068231
K94 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
S137 Phosphorylation HPRD   phospho.ELM 18669648
S138 Phosphorylation PhosphoSitePlus
T139 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S143 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
K192 Methylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
R198 Methylation PhosphoSitePlus
R205 Methylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K545 Methylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S602 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163, ...20068231
S605 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K53 Q53 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S122 G122 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T139 M139 Biomuta DOID:1324 / lung cancer [ cosmic ]
S143 L143 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S160 N160 Biomuta DOID:1324 / lung cancer [ tcga ]
S173 P173 Biomuta DOID:363 / uterine cancer [ tcga ]
R198 W198 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R198 Q198 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K215 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S235 F235 Biomuta DOID:1909 / melanoma [ tcga ]