Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92917 / GPKOW_HUMAN
Protein Name G-patch domain and KOW motifs-containing protein
Gene Name Name: GPKOW
Synonyms:GPATC5,GPATCH5,T54;
Organism Homo sapiens (Human)

PRO ID PR:Q92917
DAG View
PRO Name G-patch domain and KOW motifs-containing protein (human)
Definition A G-patch domain and KOW motifs-containing protein that is encoded in the genome of human.
Short Label hGPKOW
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92917 (GPKOW) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
T12 O-Glycosylation GlyGen 23301498, 28657654, 29237092, ...30059200
T12 Phosphorylation PhosphoSitePlus
S15 O-Glycosylation GlyGen 23301498, 28657654, 29237092, ...30059200
S20 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
S27 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   RLIMS-P   UniProt 21880142
S35 Phosphorylation PhosphoSitePlus   UniProt 23186163
S42 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18452278, 19651622, ...18669648, 20068231
K46 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
S90 Phosphorylation HPRD   PhosphoSitePlus 18491316
T91 Phosphorylation HPRD   PhosphoSitePlus 18491316
S102 Phosphorylation HPRD   PhosphoSitePlus 18491316
K106 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus   UniProt 23186163
C137 S-Nitrosylation dbSNO 26338901
T138 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
R173 Methylation PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
K192 Acetylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T216 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18220336, 18669648, ...24275569, 19690332, 20068231
S251 Phosphorylation PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K315 Methylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
T316 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   RLIMS-P   UniProt 21880142
Y323 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
K346 Acetylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
S388 Phosphorylation HPRD   PhosphoSitePlus 20068231
S471 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 24275569, 17081983, 20068231
T473 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 D2 Biomuta DOID:363 / uterine cancer [ tcga ]
C137 * Biomuta DOID:3571 / liver cancer [ icgc ]
R173 W173 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
S251 Y251 Biomuta DOID:363 / uterine cancer [ tcga ]
Y258 F258 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y258 C258 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S329 L329 Biomuta DOID:1909 / melanoma [ tcga ]
K346 N346 Biomuta DOID:363 / uterine cancer [ tcga ]