Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WX92 / NELFB_HUMAN
Protein Name Negative elongation factor B
Gene Name Name: NELFB
Synonyms:COBRA1;
Organism Homo sapiens (Human)

PRO ID PR:Q8WX92
DAG View
PRO Name negative elongation factor B (human)
Definition A negative elongation factor B that is encoded in the genome of human.
Short Label hNELFB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WX92 (NELFB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T56 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K519 Acetylation PhosphoSitePlus   UniProt 19608861
K519 Ubiquitination PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
Y541 Phosphorylation PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
S557 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 24275569, 19690332, 20068231
T564 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K92 N92 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K99 N99 Biomuta DOID:1612 / breast cancer [ cosmic ]
S100 R100 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S557 I557 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]