iPTMnet Report for Q8WU10 (PYROXD1)
Protein Information
UniProt AC / UniProt ID | Q8WU10 / PYRD1_HUMAN |
Protein Name | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 |
Gene Name | Name: PYROXD1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WU10 |
PRO Name | pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (human) |
Definition | A pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hPYROXD1 |
Category | organism-gene |
Q8WU10 (PYROXD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K225 | Acetylation | score1 | PhosphoSitePlus | |||
K227 | Acetylation | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y354 | Phosphorylation | score1 | PhosphoSitePlus | |||
S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y446 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K88 | N88 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K91 | N91 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K287 | T287 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |