Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TF40 / FNIP1_HUMAN
Protein Name Folliculin-interacting protein 1
Gene Name Name: FNIP1
Synonyms:KIAA1961;
Organism Homo sapiens (Human)

PRO ID PR:Q8TF40
DAG View
PRO Name folliculin-interacting protein 1 (human)
Definition A folliculin-interacting protein 1 that is encoded in the genome of human.
Short Label hFNIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TF40 (FNIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S230 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus   UniProt 23186163
S296 Phosphorylation PhosphoSitePlus   UniProt 23186163
K484 Ubiquitination PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus
Y510 Phosphorylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus   UniProt 18669648
S594 Phosphorylation PhosphoSitePlus   UniProt 18669648
Y612 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
S758 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
S763 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
T848 Phosphorylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
S860 Phosphorylation PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
K879 Ubiquitination PhosphoSitePlus
K918 Ubiquitination PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus
K924 Ubiquitination PhosphoSitePlus
S938 O-Glycosylation GlyGen   UniProt 30699359
S938 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 30699359
S939 Phosphorylation PhosphoSitePlus   UniProt 30699359
S941 Phosphorylation PhosphoSitePlus   UniProt 30699359
S946 Phosphorylation PhosphoSitePlus   UniProt 30699359
S948 Phosphorylation PhosphoSitePlus   UniProt 30699359
K1119 Ubiquitination PhosphoSitePlus   UniProt 30699359
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation HPRD 20068231
S220 Phosphorylation HPRD 19664994
S261 Phosphorylation HPRD 18669648
S263 Phosphorylation HPRD 18669648
S264 Phosphorylation HPRD 18669648
S272 Phosphorylation HPRD 18669648
S276 Phosphorylation HPRD 18669648
T278 Phosphorylation HPRD 18669648
S593 Phosphorylation HPRD 19651622, 18669648, 20068231
S594 Phosphorylation HPRD 19651622, 18669648, 20068231
S760 Phosphorylation HPRD 18669648, 20068231
S763 Phosphorylation HPRD 18669648, 20068231
T765 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation HPRD 20068231
S233 Phosphorylation HPRD 18669648
S235 Phosphorylation HPRD 18669648
S236 Phosphorylation HPRD 18669648
S244 Phosphorylation HPRD 18669648
S248 Phosphorylation HPRD 18669648
T250 Phosphorylation HPRD 18669648
S565 Phosphorylation HPRD 19651622, 18669648, 20068231
S566 Phosphorylation HPRD 19651622, 18669648, 20068231
S732 Phosphorylation HPRD 18669648, 20068231
S735 Phosphorylation HPRD 18669648, 20068231
T737 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K147 N147 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S220 C220 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S230 N230 Biomuta DOID:363 / uterine cancer [ tcga ]
S254 R254 Biomuta DOID:263 / kidney cancer [ tcga ]
S264 R264 Biomuta DOID:3571 / liver cancer [ icgc ]
S276 A276 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S292 R292 Biomuta DOID:3571 / liver cancer [ icgc ]
S292 N292 Biomuta DOID:3963 / thyroid carcinoma [ icgc ]
S594 T594 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y612 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K876 Q876 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]