Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TB92 / HMGC2_HUMAN
Protein Name 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
Gene Name Name: HMGCLL1
Organism Homo sapiens (Human)

PRO ID PR:Q8TB92
DAG View
PRO Name 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
Definition A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of human.
Short Label hHMGCLL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TB92 (HMGCLL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 22865860
S13 Phosphorylation PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
G2 E2 Biomuta DOID:263 / kidney cancer [ cosmic ]
K260 Q260 Biomuta DOID:363 / uterine cancer [ tcga ]