Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N264 / RHG24_HUMAN
Protein Name Rho GTPase-activating protein 24
Gene Name Name: ARHGAP24
Synonyms:FILGAP;
Organism Homo sapiens (Human)

PRO ID PR:Q8N264
DAG View
PRO Name Rho GTPase-activating protein 24 (human)
Definition A Rho GTPase-activating protein 24 that is encoded in the genome of human.
Short Label hARHGAP24
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N264 (ARHGAP24) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T62 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S391 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16862148
T393 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
S402 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 26359494, 16862148
S406 Phosphorylation PhosphoSitePlus
S413 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16862148
S415 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16862148, 23186163
K421 Acetylation PhosphoSitePlus
K422 Acetylation PhosphoSitePlus
S437 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16862148
T452 Phosphorylation Q13464 (ROCK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16862148
S464 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
S573 Phosphorylation Q13464 (ROCK1) Signor 16862148
S574 Phosphorylation Q13464 (ROCK1) Signor 16862148
T575 Phosphorylation Q13464 (ROCK1) Signor 16862148
T576 Phosphorylation Q13464 (ROCK1) Signor 16862148
T577 Phosphorylation Q13464 (ROCK1) Signor 16862148
T624 Phosphorylation PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
T728 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S391 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S402 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S413 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S415 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S437 Phosphorylation Q13464 (ROCK1) HPRD 16862148
T452 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S573 Phosphorylation Q13464 (ROCK1) HPRD 16862148
S574 Phosphorylation Q13464 (ROCK1) HPRD 16862148
T575 Phosphorylation Q13464 (ROCK1) HPRD 16862148
T576 Phosphorylation Q13464 (ROCK1) HPRD 16862148
T577 Phosphorylation Q13464 (ROCK1) HPRD 16862148


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S369 N369 Biomuta DOID:1909 / melanoma [ cosmic ]
S391 F391 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K422 N422 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T577 P577 Biomuta DOID:1612 / breast cancer [ icgc ]
T728 M728 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ]