Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZF2 / AGRF5_HUMAN
Protein Name Adhesion G protein-coupled receptor F5 precursor
Gene Name Name: ADGRF5
Synonyms:GPR116,KIAA0758;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZF2
DAG View
PRO Name adhesion G protein-coupled receptor F5 (human)
Definition An adhesion G protein-coupled receptor F5 that is encoded in the genome of human.
Short Label hADGRF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZF2 (ADGRF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
N179 N-Glycosylation GlyGen 29391424
Y209 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
T236 O-Glycosylation GlyGen 30459171
N256 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424
N301 N-Glycosylation GlyGen 29671580, 29391424
N315 N-Glycosylation GlyGen   UniProt 16335952, 29391424
Y322 Phosphorylation PhosphoSitePlus
N328 N-Glycosylation GlyGen 29391424
N339 N-Glycosylation GlyGen 29391424
N398 N-Glycosylation GlyGen 29391424
T474 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
N505 N-Glycosylation GlyGen 29391424
N540 N-Glycosylation GlyGen 29391424
T604 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
N627 N-Glycosylation GlyGen 23090970, 29391424
N650 N-Glycosylation GlyGen 29391424
S656 Phosphorylation PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
N718 N-Glycosylation GlyGen 29391424
N820 N-Glycosylation GlyGen 23090970, 29391424
S939 Phosphorylation PhosphoSitePlus
T941 Phosphorylation PhosphoSitePlus
S1123 Phosphorylation PhosphoSitePlus
S1125 Phosphorylation PhosphoSitePlus
N1160 N-Glycosylation GlyGen 29391424
S1306 Phosphorylation PhosphoSitePlus
S1307 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T604 Phosphorylation HPRD 18452278
S607 Phosphorylation HPRD 18452278
S608 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N339 K339 Biomuta DOID:3571 / liver cancer [ icgc ]
T474 K474 Biomuta DOID:363 / uterine cancer [ tcga ]
T604 M604 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S607 * Biomuta DOID:3571 / liver cancer [ icgc ]
N650 S650 Biomuta DOID:1324 / lung cancer [ icgc, tcga ]
S698 N698 Biomuta DOID:1612 / breast cancer [ icgc ]
S1123 N1123 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1125 F1125 Biomuta DOID:1909 / melanoma [ tcga ] DOID:3070 / malignant glioma [ tcga ]
S1306 C1306 Biomuta DOID:263 / kidney cancer [ tcga ]
S1307 Y1307 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]