Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86Y13 / DZIP3_HUMAN
Protein Name E3 ubiquitin-protein ligase DZIP3
Gene Name Name: DZIP3
Synonyms:KIAA0675;
Organism Homo sapiens (Human)

PRO ID PR:Q86Y13
DAG View
PRO Name E3 ubiquitin-protein ligase DZIP3 (human)
Definition An E3 ubiquitin-protein ligase DZIP3 that is encoded in the genome of human.
Short Label hDZIP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86Y13 (DZIP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
K635 Ubiquitination PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
K663 Acetylation PhosphoSitePlus
K664 Acetylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
K718 Ubiquitination PhosphoSitePlus
K738 Ubiquitination PhosphoSitePlus
K748 Ubiquitination PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
K768 Methylation PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
K821 Ubiquitination PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
K830 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
K851 Ubiquitination PhosphoSitePlus
K883 Ubiquitination PhosphoSitePlus
K936 Ubiquitination PhosphoSitePlus
K1042 Ubiquitination PhosphoSitePlus
K1051 Ubiquitination PhosphoSitePlus
T1054 Phosphorylation PhosphoSitePlus
K1061 Ubiquitination PhosphoSitePlus
K1066 Ubiquitination PhosphoSitePlus
S1081 Phosphorylation PhosphoSitePlus
K1087 Ubiquitination PhosphoSitePlus
K1088 Ubiquitination PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
S1103 Phosphorylation PhosphoSitePlus
K1118 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K36 T36 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K55 N55 Biomuta DOID:363 / uterine cancer [ tcga ]
K315 N315 Biomuta DOID:363 / uterine cancer [ tcga ]
K372 N372 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K376 Q376 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K664 E664 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K684 N684 Biomuta DOID:11934 / head and neck cancer [ tcga ]
K703 I703 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K703 Q703 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S707 G707 Biomuta DOID:363 / uterine cancer [ tcga ]
K718 R718 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:3571 / liver cancer [ tcga ]
K786 E786 Biomuta DOID:363 / uterine cancer [ tcga ]
K821 N821 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K846 E846 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K1087 N1087 Biomuta DOID:363 / uterine cancer [ tcga ]