Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86WS5 / TMPSC_HUMAN
Protein Name Transmembrane protease serine 12 precursor
Gene Name Name: TMPRSS12
Organism Homo sapiens (Human)

PRO ID PR:Q86WS5
DAG View
PRO Name transmembrane protease serine 12 (human)
Definition A transmembrane protease serine 12 that is encoded in the genome of human.
Short Label hTMPRSS12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86WS5 (TMPRSS12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 W24 Biomuta DOID:263 / kidney cancer [ tcga ]
Y243 C243 Biomuta DOID:363 / uterine cancer [ cosmic ]
T263 A263 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]