Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86TB3 / ALPK2_HUMAN
Protein Name Alpha-protein kinase 2
Gene Name Name: ALPK2
Synonyms:HAK;
Organism Homo sapiens (Human)

PRO ID PR:Q86TB3
DAG View
PRO Name alpha-protein kinase 2 (human)
Definition An alpha-protein kinase 2 that is encoded in the genome of human.
Short Label hALPK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86TB3 (ALPK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K528 Acetylation PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S1078 Phosphorylation PhosphoSitePlus
K1260 Ubiquitination PhosphoSitePlus
K1419 Ubiquitination PhosphoSitePlus
S1602 Phosphorylation PhosphoSitePlus
K1697 Ubiquitination PhosphoSitePlus
K1712 Ubiquitination PhosphoSitePlus
K1728 Ubiquitination PhosphoSitePlus
K1750 Ubiquitination PhosphoSitePlus
K1826 Ubiquitination PhosphoSitePlus
K1861 Ubiquitination PhosphoSitePlus
T1868 Phosphorylation PhosphoSitePlus
Y1975 Phosphorylation PhosphoSitePlus
K1976 Ubiquitination PhosphoSitePlus
K2046 Ubiquitination PhosphoSitePlus
T2089 Phosphorylation PhosphoSitePlus
T2095 Phosphorylation PhosphoSitePlus
K2098 Ubiquitination PhosphoSitePlus
K2123 Ubiquitination PhosphoSitePlus
K2131 Ubiquitination PhosphoSitePlus
K2141 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K1750 N1750 Biomuta DOID:363 / uterine cancer [ icgc, tcga ] DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K1826 R1826 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
Y1975 * Biomuta DOID:3571 / liver cancer [ icgc ]
T2095 M2095 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:2531 / hematologic cancer [ icgc ]
K2141 E2141 Biomuta DOID:9256 / colorectal cancer [ tcga ]