Protein Information

Cytoscape View

UniProt AC / UniProt ID Q7Z6A9 / BTLA_HUMAN
Protein Name B- and T-lymphocyte attenuator precursor
Gene Name Name: BTLA
Organism Homo sapiens (Human)

DAG View
PRO Name B- and T-lymphocyte attenuator (human)
Definition A B- and T-lymphocyte attenuator that is encoded in the genome of human.
Short Label hBTLA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q7Z6A9 (BTLA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N75 N-Glycosylation GlyGen 24190977
S216 Phosphorylation PhosphoSitePlus
Y226 Phosphorylation PRO   PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation IntAct   PRO   PhosphoSitePlus 14652006
S263 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation IntAct   PRO   PhosphoSitePlus 14652006


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046521 (hBTLA/SigPep-/Phos:1) pY226,pY257,pY282 PRO

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q7Z6A9 (BTLA) Y282 P29350 (PTPN6) unknown eFIP 14652006
Phosphorylation Q7Z6A9 (BTLA) Y282 Q06124 (PTPN11) unknown eFIP 14652006

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S263 Y263 Biomuta DOID:1324 / lung cancer [ cosmic ]