Protein Information

Cytoscape View


UniProt AC / UniProt ID Q76LX8 / ATS13_HUMAN
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 13 precursor
Gene Name Name: ADAMTS13
Synonyms:C9orf8;ORFNames:UNQ6102/PRO20085;
Organism Homo sapiens (Human)

PRO ID PR:Q76LX8
DAG View
PRO Name a disintegrin and metalloproteinase with thrombospondin motifs 13 (human)
Definition An a disintegrin and metalloproteinase with thrombospondin motifs 13 that is encoded in the genome of human.
Short Label hADAMTS13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q76LX8 (ADAMTS13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T358 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
N552 N-Glycosylation UniProt 19880749
N614 N-Glycosylation UniProt 16335952, 19880749
N667 N-Glycosylation UniProt 16335952, 19139490
S696 Phosphorylation PhosphoSitePlus
S698 O-Glycosylation UniProt 17395589
S698 Phosphorylation PhosphoSitePlus
N707 N-Glycosylation UniProt 19139490
S757 O-Glycosylation UniProt 17395589
S907 O-Glycosylation UniProt 17395589
S965 O-Glycosylation UniProt 17395589
S1027 O-Glycosylation UniProt 17395589
S1087 O-Glycosylation UniProt 17395589
T1294 Phosphorylation PhosphoSitePlus
Y1296 Phosphorylation PhosphoSitePlus
N1354 N-Glycosylation UniProt 16335952
S1356 Phosphorylation PhosphoSitePlus
Y1357 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N707 K707 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1087 F1087 Biomuta DOID:1324 / lung cancer [ icgc ]
Y1296 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]