Protein Information

Cytoscape View

UniProt AC / UniProt ID Q6ZWH5 / NEK10_HUMAN
Protein Name Serine/threonine-protein kinase Nek10
Gene Name Name: NEK10
Organism Homo sapiens (Human)

DAG View
PRO Name serine/threonine-protein kinase Nek10 (human)
Definition A serine/threonine-protein kinase Nek10 that is encoded in the genome of human.
Short Label hNEK10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q6ZWH5 (NEK10) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K42 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
S358 Phosphorylation RLIMS-P 31124786
Y583 Phosphorylation PhosphoSitePlus
Y590 Phosphorylation PhosphoSitePlus
Y591 Phosphorylation PhosphoSitePlus
Y644 Phosphorylation RLIMS-P 31124786

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y591 F591 Biomuta DOID:1324 / lung cancer [ tcga ]
Y591 * Biomuta DOID:9256 / colorectal cancer [ tcga ]