Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6ZN28 / MACC1_HUMAN
Protein Name Metastasis-associated in colon cancer protein 1
Gene Name Name: MACC1
Organism Homo sapiens (Human)

PRO ID PR:Q6ZN28
DAG View
PRO Name metastasis-associated in colon cancer protein 1 (human)
Definition A metastasis-associated in colon cancer protein 1 that is encoded in the genome of human.
Short Label hMACC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6ZN28 (MACC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus   UniProt 23186163
S34 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
Y568 Phosphorylation PhosphoSitePlus
Y572 Phosphorylation PhosphoSitePlus
K645 Acetylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
Y803 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 C74 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
S115 T115 Biomuta DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S413 Y413 Biomuta DOID:3571 / liver cancer [ icgc ]
S515 L515 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S533 P533 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K645 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]