Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6UXB8 / PI16_HUMAN
Protein Name Peptidase inhibitor 16 precursor
Gene Name Name: PI16
Synonyms:CRISP9,PSPBP;ORFNames:PSEC0164,UNQ289/PRO328;
Organism Homo sapiens (Human)

PRO ID PR:Q6UXB8
DAG View
PRO Name peptidase inhibitor 16 (human)
Definition A peptidase inhibitor 16 that is encoded in the genome of human.
Short Label hPI16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6UXB8 (PI16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation PhosphoSitePlus
N114 N-Glycosylation GlyGen 23090970
T119 O-Glycosylation GlyGen 30459171
K174 Ubiquitination PhosphoSitePlus
T214 O-Glycosylation GlyGen 30459171
S249 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
T285 O-Glycosylation GlyGen 30459171
S296 O-Glycosylation GlyGen 30459171
S310 O-Glycosylation GlyGen 30459171
T311 O-Glycosylation GlyGen 30459171
S330 O-Glycosylation PhosphoSitePlus
S336 O-Glycosylation PhosphoSitePlus
S372 O-Glycosylation GlyGen 30459171
T386 O-Glycosylation GlyGen 30459171, 22171320
T390 O-Glycosylation GlyGen 22171320
T393 O-Glycosylation GlyGen 22171320
S394 O-Glycosylation GlyGen 22171320
S395 O-Glycosylation GlyGen 22171320


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N114 D114 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T214 S214 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S249 * Biomuta DOID:10534 / stomach cancer [ tcga ]
S249 L249 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T285 P285 Biomuta DOID:363 / uterine cancer [ tcga ]
S296 G296 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S336 Y336 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T390 M390 Biomuta DOID:3571 / liver cancer [ tcga ]