Protein Information

Cytoscape View


UniProt AC / UniProt ID Q66K74 / MAP1S_HUMAN
Protein Name Microtubule-associated protein 1S
Gene Name Name: MAP1S
Synonyms:BPY2IP1,C19orf5,MAP8,VCY2IP1;
Organism Homo sapiens (Human)

PRO ID PR:Q66K74
DAG View
PRO Name microtubule-associated protein 1S (human)
Definition A microtubule-associated protein 1S that is encoded in the genome of human.
Short Label hMAP1S
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q66K74 (MAP1S) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K380 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...17081983
S475 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T490 Phosphorylation PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
K552 Methylation PhosphoSitePlus
K553 Methylation PhosphoSitePlus
T554 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus   UniProt 23186163
S592 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
T638 Phosphorylation PhosphoSitePlus   UniProt 23186163
S640 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S643 Phosphorylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus   UniProt 23186163
S657 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...24275569
T671 Phosphorylation PhosphoSitePlus
T673 Phosphorylation PhosphoSitePlus
T676 Phosphorylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus   UniProt 19369195, 21406692, 23186163, ...18220336, 18669648, 24275569, 20068231
S762 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T782 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231, 24275569
T813 Phosphorylation PhosphoSitePlus
T852 Phosphorylation PhosphoSitePlus
R854 Methylation PhosphoSitePlus
R861 Methylation PhosphoSitePlus
R863 Methylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
T879 Phosphorylation PhosphoSitePlus
T886 Phosphorylation PhosphoSitePlus
K887 Methylation PhosphoSitePlus
R894 Methylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus   RLIMS-P 30266825
S903 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
R926 Methylation PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
R935 Methylation PhosphoSitePlus
T941 Phosphorylation PhosphoSitePlus
S999 Phosphorylation PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation HPRD 20068231
S472 Phosphorylation HPRD 19651622, 18669648, 20068231
S475 Phosphorylation HPRD 18669648
S582 Phosphorylation HPRD 20068231
S631 Phosphorylation HPRD 18669648, 20068231
T638 Phosphorylation HPRD 19651622, 20166139, 18669648, ...15302935, 20068231
S640 Phosphorylation HPRD 19651622, 20166139, 18669648, ...15302935, 20068231
S643 Phosphorylation HPRD 18669648
S657 Phosphorylation HPRD 18691976, 20058876, 19664994, ...15302935, 18669648, 18767875, 20068231, 20068230
S729 Phosphorylation HPRD 20166139, 18669648
S731 Phosphorylation HPRD 20166139, 18669648
S741 Phosphorylation HPRD 18669648
S759 Phosphorylation HPRD 19413330, 18691976, 20058876, ...15302935, 19664994, 19664995, 18669648, 16055720, 20166139, 19415658, 20068231
S762 Phosphorylation HPRD 19413330, 18691976, 19664995, ...19651622, 18669648, 19415658
S788 Phosphorylation HPRD 18669648, 20058876
S790 Phosphorylation HPRD 20058876
S809 Phosphorylation HPRD 18669648, 20058876, 20068231
T813 Phosphorylation HPRD 19413330, 18669648, 20058876
S838 Phosphorylation HPRD 20068231
S900 Phosphorylation HPRD 17287340
S906 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K552 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T554 M554 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S582 N582 Biomuta DOID:1324 / lung cancer [ icgc ]
S762 I762 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T782 M782 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S788 N788 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
R863 Q863 Biomuta DOID:1909 / melanoma [ cosmic ]
K877 R877 Biomuta DOID:2531 / hematologic cancer [ icgc ]
R894 C894 Biomuta DOID:1115 / sarcoma [ tcga ]
S896 I896 Biomuta DOID:1115 / sarcoma [ tcga ]
R926 G926 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]