Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5TCH4 / CP4AM_HUMAN
Protein Name Cytochrome P450 4A22 precursor
Gene Name Name: CYP4A22
Organism Homo sapiens (Human)

PRO ID PR:Q5TCH4
DAG View
PRO Name cytochrome P450 4A22 (human)
Definition A cytochrome P450 4A22 that is encoded in the genome of human.
Short Label hCYP4A22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5TCH4 (CYP4A22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S4 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 F4 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S4 T4 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S4 C4 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
Y88 D88 Biomuta DOID:3571 / liver cancer [ tcga ]