iPTMnet Report for Q5TBB1 (RNASEH2B)
Protein Information
UniProt AC / UniProt ID | Q5TBB1 / RNH2B_HUMAN |
Protein Name | Ribonuclease H2 subunit B |
Gene Name | Name: RNASEH2B Synonyms:DLEU8; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5TBB1 |
PRO Name | ribonuclease H2 subunit B (human) |
Definition | A ribonuclease H2 subunit B that is encoded in the genome of human. |
Short Label | hRNASEH2B |
Category | organism-gene |
Q5TBB1 (RNASEH2B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378, 22223895 | ||
K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
T174 | Phosphorylation | score1 | PhosphoSitePlus | |||
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
K233 | Ubiquitination | score1 | PhosphoSitePlus | |||
S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K247 | Acetylation | score1 | PhosphoSitePlus | |||
K250 | Sumoylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
K259 | Sumoylation | score1 | PhosphoSitePlus | |||
K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y262 | Phosphorylation | score1 | PhosphoSitePlus | |||
T263 | Phosphorylation | score1 | PhosphoSitePlus | |||
K264 | Acetylation | score1 | PhosphoSitePlus | |||
K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
K278 | Acetylation | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
K304 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K233 | N233 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S246 | L246 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc, tcga ] | |
K259 | N259 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T263 | A263 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K284 | R284 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |