iPTMnet Report for Q2NL67 (PARP6)
Protein Information
UniProt AC / UniProt ID | Q2NL67 / PARP6_HUMAN |
Protein Name | Protein mono-ADP-ribosyltransferase PARP6 |
Gene Name | Name: PARP6 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q2NL67 |
PRO Name | protein mono-ADP-ribosyltransferase PARP6 (human) |
Definition | A protein mono-ADP-ribosyltransferase PARP6 that is encoded in the genome of human. |
Short Label | hPARP6 |
Category | organism-gene |
Q2NL67 (PARP6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S101 | Phosphorylation | score1 | PhosphoSitePlus | |||
S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y105 | Phosphorylation | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
S482 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S103 | Y103 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S352 | R352 | Biomuta | DOID:2531 / hematologic cancer [ icgc ] | |
K404 | R404 | Biomuta | DOID:363 / uterine cancer [ tcga ] |