iPTMnet Report for Q2NL67 (PARP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2NL67 / PARP6_HUMAN
Protein Name Protein mono-ADP-ribosyltransferase PARP6
Gene Name Name: PARP6
Organism Homo sapiens (Human)

PRO ID PR:Q2NL67
DAG View
PRO Name poly [ADP-ribose] polymerase 6 (human)
Definition A poly [ADP-ribose] polymerase 6 that is encoded in the genome of human.
Short Label hPARP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2NL67 (PARP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S101 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S103 Y103 Biomuta DOID:3571 / liver cancer [ icgc ]
S352 R352 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K404 R404 Biomuta DOID:363 / uterine cancer [ tcga ]