Protein Information

Cytoscape View

UniProt AC / UniProt ID Q16143 / SYUB_HUMAN
Protein Name Beta-synuclein
Gene Name Name: SNCB
Organism Homo sapiens (Human)

PRO ID PR:Q16143
DAG View
PRO Name beta-synuclein (human)
Definition A beta-synuclein that is encoded in the genome of human.
Short Label hSNCB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q16143 (SNCB) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
K12 Acetylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S118 Phosphorylation Q9H4B4 (PLK3) , P53350 (PLK1) , Q9NYY3 (PLK2) , P34947 (GRK5) HPRD   neXtProt   PhosphoSitePlus   Signor   UniProt 10852916, 21849493, 19889641
Y127 Phosphorylation O14757 (CHEK1) PhosphoSitePlus   Signor 21699177

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K21 N21 Biomuta DOID:2531 / hematologic cancer [ icgc ]