Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15413 / RYR3_HUMAN
Protein Name Ryanodine receptor 3
Gene Name Name: RYR3
Synonyms:HBRR;
Organism Homo sapiens (Human)

PRO ID PR:Q15413
DAG View
PRO Name ryanodine receptor 3 (human)
Definition A ryanodine receptor 3 that is encoded in the genome of human.
Short Label hRYR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15413 (RYR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S160 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
T633 Phosphorylation PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K828 Acetylation PhosphoSitePlus
S1036 Phosphorylation PhosphoSitePlus
S1385 Phosphorylation PhosphoSitePlus
Y1388 Phosphorylation PhosphoSitePlus
S1399 Phosphorylation PhosphoSitePlus
S1506 Phosphorylation PhosphoSitePlus
Y1578 Phosphorylation PhosphoSitePlus
Y1845 Phosphorylation PhosphoSitePlus
T1859 Phosphorylation PhosphoSitePlus
T1863 Phosphorylation PhosphoSitePlus
Y2195 Phosphorylation PhosphoSitePlus
S2197 Phosphorylation PhosphoSitePlus
S2215 Phosphorylation PhosphoSitePlus
S2251 Phosphorylation PhosphoSitePlus
S2268 Phosphorylation PhosphoSitePlus
S2403 Phosphorylation PhosphoSitePlus
T2448 Phosphorylation PhosphoSitePlus
Y2450 Phosphorylation PhosphoSitePlus
S2591 Phosphorylation PhosphoSitePlus
Y3263 Phosphorylation PhosphoSitePlus
S3523 Phosphorylation PhosphoSitePlus
T3715 Phosphorylation PhosphoSitePlus
S4527 Phosphorylation PhosphoSitePlus
Y4562 Phosphorylation PhosphoSitePlus
T4655 Phosphorylation PhosphoSitePlus
T4658 Phosphorylation PhosphoSitePlus
S4661 Phosphorylation PhosphoSitePlus
T4664 Phosphorylation PhosphoSitePlus
Y4682 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K658 N658 Biomuta DOID:363 / uterine cancer [ tcga ]
K828 N828 Biomuta DOID:8618 / oral cavity cancer [ icgc ]
S1385 N1385 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1388 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y2195 * Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S2268 I2268 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S3523 F3523 Biomuta DOID:1115 / sarcoma [ tcga ]
S4527 C4527 Biomuta DOID:1324 / lung cancer [ tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
Y4682 H4682 Biomuta DOID:363 / uterine cancer [ cosmic ]