Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15397 / PUM3_HUMAN
Protein Name Pumilio homolog 3
Gene Name Name: PUM3
Synonyms:cPERP-C;
Organism Homo sapiens (Human)

PRO ID PR:Q15397
DAG View
PRO Name pumilio homolog 3 (human)
Definition A protein that is a translation product of the PUM3 gene in human.
Short Label hPUM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15397 (PUM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
K39 Methylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K71 Acetylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S29 C29 Biomuta DOID:1612 / breast cancer [ cosmic ]
K39 R39 Biomuta DOID:1909 / melanoma [ cosmic ]
K71 R71 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K79 N79 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K106 R106 Biomuta DOID:363 / uterine cancer [ tcga ]
K196 Q196 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K221 R221 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
Y257 C257 Biomuta DOID:1324 / lung cancer [ cosmic ]
T314 N314 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
K436 Q436 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S487 Y487 Biomuta DOID:363 / uterine cancer [ tcga ]