Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13772 / NCOA4_HUMAN
Protein Name Nuclear receptor coactivator 4
Gene Name Name: NCOA4
Synonyms:ARA70,ELE1,RFG;
Organism Homo sapiens (Human)

PRO ID PR:Q13772
DAG View
PRO Name nuclear receptor coactivator 4 (human)
Definition A nuclear receptor coactivator 4 that is encoded in the genome of human.
Short Label hNCOA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13772 (NCOA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K42 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S456 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K465 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S192 Phosphorylation HPRD 20068231
S456 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S57 I57 Biomuta DOID:1324 / lung cancer [ tcga ]
S57 N57 Biomuta DOID:1909 / melanoma [ cosmic ]
S192 P192 Biomuta DOID:1909 / melanoma [ cosmic ]
K209 T209 Biomuta DOID:4362 / cervical cancer [ tcga ]
K255 E255 Biomuta DOID:363 / uterine cancer [ tcga ]
K263 R263 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K263 E263 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K356 T356 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K447 R447 Biomuta DOID:3953 / adrenal gland cancer [ tcga ] DOID:1324 / lung cancer [ tcga ]
K475 T475 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K545 N545 Biomuta DOID:2994 / germ cell cancer [ tcga ]