Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13425 / SNTB2_HUMAN
Protein Name Beta-2-syntrophin
Gene Name Name: SNTB2
Synonyms:D16S2531E,SNT2B2,SNTL;
Organism Homo sapiens (Human)

PRO ID PR:Q13425
DAG View
PRO Name beta-2-syntrophin (human)
Definition A beta-2-syntrophin that is encoded in the genome of human.
Short Label hSNTB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13425 (SNTB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
S95 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 17081983, 23186163, ...20886068, 18669648, 24275569, 20068231, 16964243
S110 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569, 20068231
S129 Phosphorylation PhosphoSitePlus   UniProt 23186163
K131 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
K184 Methylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
K205 Acetylation PhosphoSitePlus
K206 Acetylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S208 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S211 Phosphorylation PhosphoSitePlus   UniProt 24275569
S222 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
S224 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S226 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S228 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S231 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S233 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
K235 Acetylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S389 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S393 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 20068231
S395 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
K489 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S82 Phosphorylation HPRD 20068231
S86 Phosphorylation HPRD 20068231
S95 Phosphorylation HPRD 19413330, 18691976, 18578522, ...18491316, 17081983, 19664994, 20058876, 19664995, 19651622, 18669648, 19415658, 20068231
S110 Phosphorylation HPRD 19413330, 18691976, 18578522, ...20058876, 19664994, 19664995, 18452278, 17322306, 18669648, 19651622, 18767875, 20166139, 19415658, 20068231
T201 Phosphorylation HPRD 17924679
S211 Phosphorylation HPRD 17081983
S222 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S224 Phosphorylation HPRD 18669648, 17081983, 20068231
S226 Phosphorylation HPRD 18669648
S228 Phosphorylation HPRD 18669648, 20068231
S231 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S233 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S271 Phosphorylation HPRD 20068231
S387 Phosphorylation HPRD 20068231
S389 Phosphorylation HPRD 18669648
S393 Phosphorylation HPRD 17322306, 19651622, 18669648, ...19664994, 20068231
S395 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231, 18452278
T401 Phosphorylation HPRD 17081983
T511 Phosphorylation HPRD 18691976
S516 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
S258 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S82 W82 Biomuta DOID:1612 / breast cancer [ icgc ]
T201 A201 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S211 A211 Biomuta DOID:3070 / malignant glioma [ tcga ]
S222 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S233 L233 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
S395 C395 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S395 F395 Biomuta DOID:1909 / melanoma [ icgc, tcga ]