Protein Information

Cytoscape View


UniProt AC / UniProt ID Q0JRZ9 / FCHO2_HUMAN
Protein Name F-BAR domain only protein 2
Gene Name Name: FCHO2
Organism Homo sapiens (Human)

PRO ID PR:Q0JRZ9
DAG View
PRO Name F-BAR domain only protein 2 (human)
Definition An F-BAR domain only protein 2 that is encoded in the genome of human.
Short Label hFCHO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q0JRZ9 (FCHO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y22 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
T289 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
Y323 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus   UniProt 20068231
S387 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 20068231
S391 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S394 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
S403 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...20068231
T408 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
T473 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S488 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T492 Phosphorylation phospho.ELM 18669648
S493 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T495 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S496 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S508 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S509 Phosphorylation PhosphoSitePlus
S510 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S511 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S513 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S515 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S517 Phosphorylation phospho.ELM 18669648
S519 Phosphorylation phospho.ELM 18669648
T523 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus   UniProt 20068231
S536 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
Y676 Phosphorylation PhosphoSitePlus
K678 Acetylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
K744 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T44 Phosphorylation HPRD 18452278
T385 Phosphorylation HPRD 19651622, 20068231
S387 Phosphorylation HPRD 18767875, 19664994, 16964243, ...20068231, 17081983
S391 Phosphorylation HPRD 19651622, 20068231
S394 Phosphorylation HPRD 17081983, 20068231
S403 Phosphorylation HPRD 19413330, 18767875, 19651622, ...16964243, 20068231
S478 Phosphorylation HPRD 20068231
S488 Phosphorylation HPRD 18669648, 20068231
T492 Phosphorylation HPRD 18669648
S493 Phosphorylation HPRD 18669648, 20068231
T495 Phosphorylation HPRD 18669648, 20068231
S496 Phosphorylation HPRD 18669648, 20068231
S508 Phosphorylation HPRD 18669648
S510 Phosphorylation HPRD 18669648
S511 Phosphorylation HPRD 18669648
S513 Phosphorylation HPRD 18669648
S515 Phosphorylation HPRD 18669648
S517 Phosphorylation HPRD 18669648
S519 Phosphorylation HPRD 18669648
S533 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K103 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K103 N103 Biomuta DOID:3571 / liver cancer [ icgc ]
K188 Q188 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K194 N194 Biomuta DOID:363 / uterine cancer [ tcga ]
S367 L367 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S380 Y380 Biomuta DOID:3070 / malignant glioma [ tcga ]
T408 I408 Biomuta DOID:4362 / cervical cancer [ tcga ]
S488 C488 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S508 I508 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S509 Y509 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K678 T678 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]