Protein Information

Cytoscape View


UniProt AC / UniProt ID Q0IIM8 / TBC8B_HUMAN
Protein Name TBC1 domain family member 8B
Gene Name Name: TBC1D8B
Organism Homo sapiens (Human)

PRO ID PR:Q0IIM8
DAG View
PRO Name TBC1 domain family member 8B (human)
Definition A TBC1 domain family member 8B that is encoded in the genome of human.
Short Label hTBC1D8B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q0IIM8 (TBC1D8B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y34 Phosphorylation PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
T429 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
Y753 Phosphorylation PhosphoSitePlus
Y758 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
Y771 Phosphorylation PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
Y803 Phosphorylation PhosphoSitePlus
S953 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
K1105 Acetylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K118 E118 Biomuta DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S358 T358 Biomuta DOID:363 / uterine cancer [ tcga ]
K716 E716 Biomuta DOID:363 / uterine cancer [ tcga ]
S749 * Biomuta DOID:363 / uterine cancer [ tcga ]
Y758 C758 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
S763 I763 Biomuta DOID:363 / uterine cancer [ tcga ]
S763 N763 Biomuta DOID:363 / uterine cancer [ tcga ]