Protein Information

Cytoscape View


UniProt AC / UniProt ID Q02818 / NUCB1_HUMAN
Protein Name Nucleobindin-1 precursor
Gene Name Name: NUCB1
Synonyms:NUC;
Organism Homo sapiens (Human)

PRO ID PR:Q02818
DAG View
PRO Name nucleobindin-1 (human)
Definition A nucleobindin-1 that is encoded in the genome of human.
Short Label hNUCB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q02818 (NUCB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD   PhosphoSitePlus 20068231
T39 O-Glycosylation GlyGen   PhosphoSitePlus 30459171, 30059200, 29351928, ...28510447, 22661428
T42 O-Glycosylation GlyGen   PhosphoSitePlus 30459171, 30059200, 29351928, ...28510447, 22661428
S44 O-Glycosylation GlyGen   PhosphoSitePlus 30459171, 30059200, 29351928, ...28510447, 22661428
S44 Phosphorylation PhosphoSitePlus
T47 O-Glycosylation GlyGen   PhosphoSitePlus 29351928, 28510447, 30059200, ...22661428
T47 Phosphorylation PhosphoSitePlus
Y50 O-Glycosylation GlyGen 23584533, 23399548, 25813380
Y51 O-Glycosylation GlyGen 23584533, 25813380
Y54 O-Glycosylation GlyGen 25813380
T64 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
S86 Phosphorylation HPRD   PhosphoSitePlus   UniProt 26091039, 20068231
S93 O-Glycosylation PhosphoSitePlus
S93 Phosphorylation HPRD   PhosphoSitePlus 20068231
T148 O-Glycosylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
T160 O-Glycosylation PhosphoSitePlus
T162 O-Glycosylation PhosphoSitePlus
Y168 O-Glycosylation GlyGen 23584533, 25813380
Y168 Phosphorylation PhosphoSitePlus
K177 Acetylation PhosphoSitePlus
Y179 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
Y190 O-Glycosylation GlyGen 25813380
Y190 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S224 O-Glycosylation PhosphoSitePlus
S224 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
K229 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
R310 Methylation PhosphoSitePlus
T313 O-Glycosylation PhosphoSitePlus
S320 O-Glycosylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
T321 O-Glycosylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
S369 O-Glycosylation PhosphoSitePlus
S369 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20166139, 17525332, 18077418, ...26091039
T372 O-Glycosylation PhosphoSitePlus
T372 Phosphorylation HPRD   PhosphoSitePlus 20166139
S378 O-Glycosylation PhosphoSitePlus
T426 O-Glycosylation PhosphoSitePlus
S444 O-Glycosylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 F4 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T64 M64 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T160 M160 Biomuta DOID:3070 / malignant glioma [ icgc ]
S224 I224 Biomuta DOID:3571 / liver cancer [ icgc ]
S224 C224 Biomuta DOID:2596 / larynx cancer [ cosmic ]
T313 A313 Biomuta DOID:363 / uterine cancer [ tcga ]
S444 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]