Protein Information

Cytoscape View

UniProt AC / UniProt ID Q02543 / RL18A_HUMAN
Protein Name 60S ribosomal protein L18a
Gene Name Name: RPL18A
Organism Homo sapiens (Human)

PRO ID PR:Q02543
DAG View
PRO Name 60S ribosomal protein L18a (human)
Definition A 60S ribosomal protein L18a that is encoded in the genome of human.
Short Label hRPL18A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q02543 (RPL18A) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
K2 Sumoylation PhosphoSitePlus
K2 Ubiquitination PhosphoSitePlus
S4 Phosphorylation HPRD 20068231
T6 Phosphorylation PhosphoSitePlus
R8 Methylation PhosphoSitePlus
Y10 Phosphorylation PhosphoSitePlus
K11 Sumoylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
C22 S-Nitrosylation dbSNO 26338901
T24 Phosphorylation HPRD   PhosphoSitePlus 18691976
R31 Methylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
Y63 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455, 18669648
C64 S-Nitrosylation dbSNO 26338901, 22126794
K70 Ubiquitination PhosphoSitePlus
S71 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19369195, 23186163, 17081983, ...18691976, 19415658, 18669648, 20166139, 19690332, 20068231
K76 Acetylation PhosphoSitePlus
K76 Sumoylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
T101 O-Glycosylation GlyGen 21740066, 29351928, 20305658, ...32119511, 28510447, 22121020
C109 S-Nitrosylation dbSNO 26338901, 22126794
S123 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17322306, 18691976, 18669648, ...20068231
K128 Methylation PhosphoSitePlus
K128 Sumoylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
C137 S-Nitrosylation dbSNO 26338901
K143 Ubiquitination PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
K170 Sumoylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R31 Q31 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K41 E41 Biomuta DOID:363 / uterine cancer [ tcga ]
Y63 C63 Biomuta DOID:363 / uterine cancer [ tcga ]
S71 F71 Biomuta DOID:1909 / melanoma [ tcga ]
K76 N76 Biomuta DOID:363 / uterine cancer [ tcga ]
K76 E76 Biomuta DOID:4362 / cervical cancer [ tcga ]
C109 * Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K170 E170 Biomuta DOID:363 / uterine cancer [ tcga ]