Protein Information

Cytoscape View


UniProt AC / UniProt ID Q01968 / OCRL_HUMAN
Protein Name Inositol polyphosphate 5-phosphatase OCRL
Gene Name Name: OCRL
Synonyms:OCRL1;
Organism Homo sapiens (Human)

PRO ID PR:Q01968
DAG View
PRO Name inositol polyphosphate 5-phosphatase OCRL (human)
Definition An inositol polyphosphate 5-phosphatase OCRL that is encoded in the genome of human.
Short Label hOCRL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q01968 (OCRL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K127 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K701 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K127 N127 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K127 R127 Biomuta DOID:2994 / germ cell cancer [ tcga ]
T346 I346 Biomuta DOID:363 / uterine cancer [ tcga ]
K545 N545 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K701 R701 Biomuta DOID:363 / uterine cancer [ tcga ]
K713 N713 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
T880 N880 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]