Protein Information

Cytoscape View


UniProt AC / UniProt ID P54707 / AT12A_HUMAN
Protein Name Potassium-transporting ATPase alpha chain 2
Gene Name Name: ATP12A
Synonyms:ATP1AL1;
Organism Homo sapiens (Human)

PRO ID PR:P54707
DAG View
PRO Name potassium-transporting ATPase alpha chain 2 (human)
Definition A potassium-transporting ATPase alpha chain 2 that is encoded in the genome of human.
Short Label hATP12A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54707 (ATP12A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
K459 Acetylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
T638 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K856 Acetylation PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
Y1038 Phosphorylation PhosphoSitePlus
Y1039 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 20068231
S10 Phosphorylation HPRD 20068231
S94 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T5 I5 Biomuta DOID:363 / uterine cancer [ tcga ]
S10 Y10 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S94 F94 Biomuta DOID:1909 / melanoma [ tcga ]
T101 M101 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T101 K101 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K627 N627 Biomuta DOID:3571 / liver cancer [ icgc ]
K856 N856 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
S985 F985 Biomuta DOID:1909 / melanoma [ icgc, tcga ]