Protein Information

Cytoscape View


UniProt AC / UniProt ID P49335 / PO3F4_HUMAN
Protein Name POU domain, class 3, transcription factor 4
Gene Name Name: POU3F4
Synonyms:BRN4,OTF9;
Organism Homo sapiens (Human)

PRO ID PR:P49335
DAG View
PRO Name POU domain, class 3, transcription factor 4 (human)
Definition A POU domain, class 3, transcription factor 4 that is encoded in the genome of human.
Short Label hPOU3F4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49335 (POU3F4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K249 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S265 C265 Biomuta DOID:1324 / lung cancer [ cosmic ]
S265 R265 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
S265 T265 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S268 T268 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]