iPTMnet Report for P42765 (ACAA2)
Protein Information
UniProt AC / UniProt ID | P42765 / THIM_HUMAN |
Protein Name | 3-ketoacyl-CoA thiolase, mitochondrial |
Gene Name | Name: ACAA2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P42765 |
PRO Name | 3-ketoacyl-CoA thiolase, mitochondrial (human) |
Definition | A 3-ketoacyl-CoA thiolase, mitochondrial that is encoded in the genome of human. |
Short Label | hACAA2 |
Category | organism-gene |
P42765 (ACAA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K13 | Acetylation | score1 | PhosphoSitePlus | |||
Y20 | Phosphorylation | score1 | PhosphoSitePlus | |||
K25 | Acetylation | score1 | PhosphoSitePlus | |||
K38 | Acetylation | score1 | PhosphoSitePlus | |||
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
K81 | Acetylation | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
T119 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S121 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
Y127 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
K137 | Acetylation | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
S140 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K181 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y182 | Phosphorylation | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y198 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Acetylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
K240 | Acetylation | score1 | PhosphoSitePlus | |||
K241 | Acetylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
K269 | Acetylation | score1 | PhosphoSitePlus | |||
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
K270 | Acetylation | score1 | PhosphoSitePlus | |||
T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
K305 | Acetylation | score1 | PhosphoSitePlus | |||
K306 | Acetylation | score1 | PhosphoSitePlus | |||
S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
S333 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
R370 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K13 | R13 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
T87 | P87 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K269 | N269 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K270 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |