Protein Information

Cytoscape View


UniProt AC / UniProt ID P29351 / PTN6_MOUSE
Protein Name Tyrosine-protein phosphatase non-receptor type 6
Gene Name Name: Ptpn6
Synonyms:Hcp,Hcph,Ptp1C;
Organism Mus musculus (Mouse)

PRO ID PR:P29351
DAG View
PRO Name tyrosine-protein phosphatase non-receptor type 6 (mouse)
Definition A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of mouse.
Short Label mPTPN6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P29351 (Ptpn6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus   UniProt 21183079
Y64 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
Y377 Phosphorylation PhosphoSitePlus   UniProt 17947660
K391 Ubiquitination PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
Y536 Phosphorylation P06240 (Lck) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21900501, 22210881, 8114715, ...17947660
T540 Phosphorylation PhosphoSitePlus
Y541 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus   RLIMS-P 27670070
Y564 Phosphorylation P25911 (Lyn) phospho.ELM   PhosphoSitePlus   RLIMS-P 20858858, 23766558, 8114715, ...30979083
S569 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y497 Phosphorylation phospho.ELM 19144319


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation B7UM99 (tir) Y511 P29351 (Ptpn6) unknown eFIP 23001144
Phosphorylation P35329 (Cd22) Y837 P29351 (Ptpn6) unknown eFIP 11551923
Phosphorylation P35329 (Cd22) Y837 P29351 (Ptpn6) unknown eFIP 9890995
Phosphorylation P43628 (KIR2DL3) Y303 P29351 (Ptpn6) unknown eFIP 9148918


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000044464 (mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1) Interaction PR:P29351 (mPTPN6) PRO 9867848
PR:000044464 (mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1) Interaction PR:P29351 (mPTPN6) PRO 9047385