Protein Information

Cytoscape View


UniProt AC / UniProt ID P16152 / CBR1_HUMAN
Protein Name Carbonyl reductase [NADPH] 1
Gene Name Name: CBR1
Synonyms:CBR,CRN,SDR21C1;
Organism Homo sapiens (Human)

PRO ID PR:P16152
DAG View
PRO Name carbonyl reductase [NADPH] 1 (human)
Definition A carbonyl reductase [NADPH] 1 that is encoded in the genome of human.
Short Label hCBR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16152 (CBR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S30 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
R42 Methylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K186 Acetylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K198 Acetylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
Y194 Phosphorylation HPRD 18083107
S205 Phosphorylation HPRD 20068231
S213 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S56 G56 Biomuta DOID:363 / uterine cancer [ tcga ]
K239 N239 Biomuta DOID:3571 / liver cancer [ icgc ]
K272 N272 Biomuta DOID:1612 / breast cancer [ tcga ]