Protein Information

Cytoscape View


UniProt AC / UniProt ID P12882 / MYH1_HUMAN
Protein Name Myosin-1
Gene Name Name: MYH1
Organism Homo sapiens (Human)

PRO ID PR:P12882
DAG View
PRO Name myosin-1 (human)
Definition A myosin-1 that is encoded in the genome of human.
Short Label hMYH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12882 (MYH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T61 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
Y353 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
Y413 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
K505 Acetylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
K638 Acetylation PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
Y719 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
K744 Acetylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
T790 Phosphorylation PhosphoSitePlus
Y820 Phosphorylation PhosphoSitePlus
K857 Methylation PhosphoSitePlus
K862 Methylation PhosphoSitePlus
S901 Phosphorylation PhosphoSitePlus
T915 Phosphorylation PhosphoSitePlus
K922 Acetylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
K955 Acetylation PhosphoSitePlus
K956 Acetylation PhosphoSitePlus
T964 Phosphorylation PhosphoSitePlus
T983 Phosphorylation HPRD   PhosphoSitePlus 20068231
T992 Phosphorylation PhosphoSitePlus
T997 Phosphorylation PhosphoSitePlus
T1023 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1046 Acetylation PhosphoSitePlus
K1085 Acetylation PhosphoSitePlus
K1087 Acetylation PhosphoSitePlus
K1097 Acetylation PhosphoSitePlus
R1130 Methylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
T1161 Phosphorylation PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
T1186 Phosphorylation PhosphoSitePlus
T1192 Phosphorylation PhosphoSitePlus
T1195 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
S1237 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1246 Acetylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
T1265 Phosphorylation PhosphoSitePlus
T1278 Phosphorylation PhosphoSitePlus
Y1291 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
T1300 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation PhosphoSitePlus
T1313 Phosphorylation PhosphoSitePlus
S1331 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
S1366 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1370 Phosphorylation PhosphoSitePlus
T1377 Phosphorylation PhosphoSitePlus
Y1379 Phosphorylation PhosphoSitePlus
T1381 Phosphorylation PhosphoSitePlus
T1387 Phosphorylation PhosphoSitePlus
K1394 Acetylation PhosphoSitePlus
K1395 Acetylation PhosphoSitePlus
K1396 Acetylation PhosphoSitePlus
T1421 Phosphorylation PhosphoSitePlus
K1448 Acetylation PhosphoSitePlus
T1467 Phosphorylation PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
T1483 Phosphorylation PhosphoSitePlus
Y1492 Phosphorylation PhosphoSitePlus
T1501 Phosphorylation PhosphoSitePlus
S1514 Phosphorylation PhosphoSitePlus
T1517 Phosphorylation PhosphoSitePlus
S1542 Phosphorylation PhosphoSitePlus
S1574 Phosphorylation PhosphoSitePlus
S1603 Phosphorylation PhosphoSitePlus
T1604 Phosphorylation PhosphoSitePlus
S1611 Phosphorylation PhosphoSitePlus
Y1647 Phosphorylation PhosphoSitePlus
S1667 Phosphorylation PhosphoSitePlus
S1702 Phosphorylation PhosphoSitePlus
S1714 Phosphorylation PhosphoSitePlus
T1722 Phosphorylation PhosphoSitePlus
T1725 Phosphorylation PhosphoSitePlus
S1726 Phosphorylation PhosphoSitePlus
T1730 Phosphorylation PhosphoSitePlus
K1731 Acetylation PhosphoSitePlus
K1758 Acetylation PhosphoSitePlus
T1764 Phosphorylation PhosphoSitePlus
K1774 Acetylation PhosphoSitePlus
S1832 O-Glycosylation GlyGen 29237092
S1832 Phosphorylation PhosphoSitePlus
K1835 Acetylation PhosphoSitePlus
T1855 Phosphorylation PhosphoSitePlus
Y1856 Phosphorylation PhosphoSitePlus
K1863 Acetylation PhosphoSitePlus
S1898 Phosphorylation PhosphoSitePlus
S1919 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y163 H163 Biomuta DOID:1324 / lung cancer [ cosmic ]
T168 I168 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y195 * Biomuta DOID:3571 / liver cancer [ icgc ]
T198 K198 Biomuta DOID:1324 / lung cancer [ tcga ]
S351 F351 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y424 * Biomuta DOID:3571 / liver cancer [ icgc ]
K505 M505 Biomuta DOID:363 / uterine cancer [ tcga ]
Y612 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y612 C612 Biomuta DOID:363 / uterine cancer [ tcga ]
T628 M628 Biomuta DOID:2394 / ovarian cancer [ tcga ]
K638 N638 Biomuta DOID:363 / uterine cancer [ tcga ]
T664 N664 Biomuta DOID:3571 / liver cancer [ icgc ]
T790 S790 Biomuta DOID:1324 / lung cancer [ tcga ]
K955 N955 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T997 I997 Biomuta DOID:363 / uterine cancer [ tcga ]
S1041 Y1041 Biomuta DOID:5041 / esophageal cancer [ tcga ] DOID:2531 / hematologic cancer [ icgc ]
K1046 T1046 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1085 N1085 Biomuta DOID:4159 / skin cancer [ icgc ]
R1130 P1130 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
R1130 W1130 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1132 A1132 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S1132 F1132 Biomuta DOID:3571 / liver cancer [ tcga ] DOID:1324 / lung cancer [ cosmic ]
S1141 Y1141 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1144 F1144 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
T1161 S1161 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T1192 K1192 Biomuta DOID:3571 / liver cancer [ icgc ]
T1192 M1192 Biomuta DOID:363 / uterine cancer [ tcga ]
K1246 N1246 Biomuta DOID:0070003 / blastoma [ cosmic ]
T1265 N1265 Biomuta DOID:3571 / liver cancer [ icgc ]
T1278 K1278 Biomuta DOID:1324 / lung cancer [ tcga ]
S1306 W1306 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S1306 L1306 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1366 Y1366 Biomuta DOID:1324 / lung cancer [ icgc ]
S1366 F1366 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ tcga ]
T1421 M1421 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1482 N1482 Biomuta DOID:363 / uterine cancer [ tcga ]
S1603 R1603 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S1667 R1667 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1702 R1702 Biomuta DOID:1324 / lung cancer [ tcga ]
T1730 N1730 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T1855 S1855 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K1863 N1863 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc ]