Protein Information

Cytoscape View


UniProt AC / UniProt ID P09471 / GNAO_HUMAN
Protein Name Guanine nucleotide-binding protein G(o) subunit alpha
Gene Name Name: GNAO1
Organism Homo sapiens (Human)

PRO ID PR:P09471
DAG View
PRO Name guanine nucleotide-binding protein G(o) subunit alpha (human)
Definition A guanine nucleotide-binding protein G(o) subunit alpha that is encoded in the genome of human.
Short Label hGNAO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09471 (GNAO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805
T4 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S253 A253 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S253 Y253 Biomuta DOID:1324 / lung cancer [ cosmic ]