Protein Information

Cytoscape View

UniProt AC / UniProt ID P07477 / TRY1_HUMAN
Protein Name Trypsin-1 precursor
Gene Name Name: PRSS1
Organism Homo sapiens (Human)

PRO ID PR:P07477
DAG View
PRO Name trypsin-1 (human)
Definition A trypsin-1 that is encoded in the genome of human.
Short Label hPRSS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P07477 (PRSS1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
Y154 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 8683601
K225 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 S8 Biomuta DOID:1324 / lung cancer [ tcga ]
K225 E225 Biomuta DOID:363 / uterine cancer [ tcga ]