Protein Information

Cytoscape View


UniProt AC / UniProt ID P05155 / IC1_HUMAN
Protein Name Plasma protease C1 inhibitor precursor
Gene Name Name: SERPING1
Synonyms:C1IN,C1NH;
Organism Homo sapiens (Human)

PRO ID PR:P05155
DAG View
PRO Name plasma protease C1 inhibitor (human)
Definition A plasma protease C1 inhibitor that is encoded in the genome of human.
Short Label hSERPING1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05155 (SERPING1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
N25 N-Glycosylation UniProt 16335952, 3756141, 14760718, ...22171320, 16040958
T47 O-Glycosylation UniProt 23234360, 22171320
T48 O-Glycosylation UniProt 3756141, 23234360, 22171320
S64 O-Glycosylation UniProt 3756141
N69 N-Glycosylation UniProt 16335952, 3756141, 19159218
T71 O-Glycosylation UniProt 3756141
N81 N-Glycosylation UniProt 3756141, 19159218
T83 O-Glycosylation UniProt 3756141
T88 O-Glycosylation UniProt 3756141
T92 O-Glycosylation UniProt 3756141
T96 O-Glycosylation UniProt 3756141
N238 N-Glycosylation UniProt 16335952, 17488724, 19159218, ...14760718, 19139490, 3756141
N253 N-Glycosylation UniProt 16335952, 19159218, 14760718, ...19139490, 12754519, 3756141
Y294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
K321 Acetylation PhosphoSitePlus
N352 N-Glycosylation UniProt 16335952, 19159218, 14760718, ...19139490, 19838169, 3756141
S375 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T48 I48 Biomuta DOID:3070 / malignant glioma [ tcga ]
S64 I64 Biomuta DOID:1115 / sarcoma [ tcga ]
Y294 C294 Biomuta DOID:9256 / colorectal cancer [ tcga ]