Protein Information

Cytoscape View


UniProt AC / UniProt ID O95343 / SIX3_HUMAN
Protein Name Homeobox protein SIX3
Gene Name Name: SIX3
Organism Homo sapiens (Human)

PRO ID PR:O95343
DAG View
PRO Name homeobox protein SIX3 (human)
Definition A homeobox protein SIX3 that is encoded in the genome of human.
Short Label hSIX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95343 (SIX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K214 N214 Biomuta DOID:9256 / colorectal cancer [ icgc ]