Protein Information

Cytoscape View


UniProt AC / UniProt ID O94886 / CSCL1_HUMAN
Protein Name CSC1-like protein 1
Gene Name Name: TMEM63A
Synonyms:KIAA0489,KIAA0792;
Organism Homo sapiens (Human)

PRO ID PR:O94886
DAG View
PRO Name CSC1-like protein 1 (human)
Definition A CSC1-like protein 1 that is encoded in the genome of human.
Short Label hTMEM63A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94886 (TMEM63A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N28 N-Glycosylation GlyGen 24190977
S85 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
T750 Phosphorylation PhosphoSitePlus
Y777 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N28 K28 Biomuta DOID:3571 / liver cancer [ icgc ]
S85 L85 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S97 L97 Biomuta DOID:363 / uterine cancer [ tcga ]
S98 L98 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S102 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
S735 C735 Biomuta DOID:1324 / lung cancer [ cosmic ]