Protein Information

Cytoscape View


UniProt AC / UniProt ID O76090 / BEST1_HUMAN
Protein Name Bestrophin-1
Gene Name Name: BEST1
Synonyms:VMD2;
Organism Homo sapiens (Human)

PRO ID PR:O76090
DAG View
PRO Name bestrophin-1 (human)
Definition A bestrophin-1 that is encoded in the genome of human.
Short Label hBEST1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O76090 (BEST1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
S358 Phosphorylation P17252 (PRKCA) , Q05655 (PRKCD) PhosphoSitePlus   RLIMS-P   Signor 19635817, 29121962
T504 Phosphorylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y148 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]