Protein Information

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UniProt AC / UniProt ID O60716 / CTND1_HUMAN
Protein Name Catenin delta-1
Gene Name Name: CTNND1
Synonyms:KIAA0384;
Organism Homo sapiens (Human)

PRO ID PR:O60716
DAG View
PRO Name catenin delta-1 (human)
Definition A catenin delta-1 that is encoded in the genome of human.
Short Label hCTNND1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60716 (CTNND1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895, 20068231
S4 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K25 Ubiquitination PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S47 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
T59 Phosphorylation PhosphoSitePlus   UniProt 23186163
T61 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
Y96 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107, 16212419
S97 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
R101 Methylation PhosphoSitePlus
Y112 Phosphorylation P06241 (FYN) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 17194753, 11777936
S125 Phosphorylation PhosphoSitePlus   UniProt 24275569
S129 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation phospho.ELM   PhosphoSitePlus 16212419
T177 Phosphorylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation P12931 (SRC) phospho.ELM   PhosphoSitePlus   RLIMS-P+ 17194753, 16212419
Y221 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y228 Phosphorylation P00533 (EGFR) , P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor 25386896, 26067913, 14996911, ...18220336, 17194753, 16212419, 29207493
S230 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 18220336
S232 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T235 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
R242 Methylation PhosphoSitePlus
S244 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
Y248 Phosphorylation PhosphoSitePlus
R249 Methylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26067913, 23186163, 24275569
Y257 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107, 16212419
S268 Phosphorylation Q02156 (PRKCE) , P49674 (CSNK1E) phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 26067913, 23186163, 17081983, ...3133391, 18220336, 21251911, 23542175, 24275569, 27516388, 21670201
S269 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 21670201, 18220336, ...18669648, 24275569, 17081983
Y280 Phosphorylation PhosphoSitePlus
S288 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 26067913, 23186163, 29735970, ...21468542, 18220336, 20564219, 18669648
Y291 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y296 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
Y302 Phosphorylation phospho.ELM   PhosphoSitePlus 16212419
T304 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
T310 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 26067913, 30808747, 17081983
S312 Phosphorylation PhosphoSitePlus
S320 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
Y321 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S331 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 23186163, ...17081983, 24275569
S352 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...24275569
K355 Acetylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
C394 S-Nitrosylation dbSNO 19483679
Y395 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
T611 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus   UniProt 24275569
C618 S-Nitrosylation dbSNO 26338901
K622 Acetylation PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
K623 Acetylation PhosphoSitePlus
K633 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
T643 Phosphorylation PhosphoSitePlus
T650 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
Y656 Phosphorylation PhosphoSitePlus
Y668 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
T720 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
R735 Methylation PhosphoSitePlus
K744 Ubiquitination PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
T799 Phosphorylation PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus   UniProt 20068231
K841 Ubiquitination PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
S847 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S857 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S859 Phosphorylation PhosphoSitePlus   UniProt 21406692
S861 Phosphorylation PhosphoSitePlus   UniProt 23186163
S862 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
Y865 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 24275569, 16212419
S868 Phosphorylation PhosphoSitePlus   UniProt 24275569
T869 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 24275569, 18220336
K878 Ubiquitination PhosphoSitePlus
S879 Phosphorylation P17612 (PRKACA) , P17252 (PRKCA) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 26067913, 17081983, 21406692, ...18158786, 22798526
K881 Ubiquitination PhosphoSitePlus
K882 Sumoylation PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
Y904 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S905 Phosphorylation PhosphoSitePlus
T906 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T916 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 26067913, 18669648, 17081983, ...20068231
S920 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 20068231
T932 Phosphorylation phospho.ELM 18669648
T933 Phosphorylation phospho.ELM 18669648
S943 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y962 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18578522, 20068231
S47 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T59 Phosphorylation HPRD 18212344
Y96 Phosphorylation HPRD 17016520, 15951569
Y174 Phosphorylation HPRD 17016520, 17389395
Y208 Phosphorylation HPRD 17389395
Y213 Phosphorylation HPRD 17016520, 17389395
Y217 Phosphorylation HPRD 17016520, 17389395
Y221 Phosphorylation HPRD 17016520
Y228 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S230 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S232 Phosphorylation HPRD 20166139
S244 Phosphorylation HPRD 18212344
S252 Phosphorylation HPRD 20166139, 18212344
Y257 Phosphorylation HPRD 17016520, 17389395, 18707149
S268 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S269 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y280 Phosphorylation HPRD 17016520, 17389395
S288 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y291 Phosphorylation HPRD 17016520, 18669648, 20068231
Y296 Phosphorylation HPRD 17016520, 20068231
S300 Phosphorylation HPRD 20068231
Y302 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231
T310 Phosphorylation HPRD 17081983
S320 Phosphorylation HPRD 18669648, 20068231
Y321 Phosphorylation HPRD 15951569, 18669648, 20068231
Y334 Phosphorylation HPRD 17016520, 15951569
S346 Phosphorylation HPRD 19664994, 17081983
S349 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S352 Phosphorylation HPRD 20166139, 17081983, 19664995
S675 Phosphorylation HPRD 18491316
T720 Phosphorylation HPRD 18491316
S811 Phosphorylation HPRD 20068231
S847 Phosphorylation HPRD 19664994
S859 Phosphorylation HPRD 20166139
S864 Phosphorylation HPRD 20166139
Y865 Phosphorylation HPRD 18707149
S868 Phosphorylation HPRD 20166139
T869 Phosphorylation HPRD 18212344
S879 Phosphorylation HPRD 17081983
S891 Phosphorylation HPRD 17081983
Y904 Phosphorylation HPRD 18707149
T906 Phosphorylation HPRD 18669648, 19664994, 19664995
T916 Phosphorylation HPRD 17081983, 20068231
S920 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation HPRD 17016520, 17389395
Y107 Phosphorylation HPRD 17389395
Y112 Phosphorylation HPRD 17016520, 17389395
Y116 Phosphorylation HPRD 17016520, 17389395
Y120 Phosphorylation HPRD 17016520
Y127 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S129 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S131 Phosphorylation HPRD 20166139
S143 Phosphorylation HPRD 18212344
S151 Phosphorylation HPRD 20166139, 18212344
Y156 Phosphorylation HPRD 17016520, 17389395, 18707149
S167 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S168 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y179 Phosphorylation HPRD 17016520, 17389395
S187 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y190 Phosphorylation HPRD 17016520, 18669648, 20068231
Y195 Phosphorylation HPRD 17016520, 20068231
S199 Phosphorylation HPRD 20068231
Y201 Phosphorylation HPRD 20068231
T203 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 17081983
S219 Phosphorylation HPRD 18669648, 20068231
Y220 Phosphorylation HPRD 15951569, 18669648, 20068231
Y233 Phosphorylation HPRD 17016520, 15951569
S245 Phosphorylation HPRD 19664994, 17081983
S248 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S251 Phosphorylation HPRD 20166139, 17081983, 19664995
S574 Phosphorylation HPRD 18491316
T619 Phosphorylation HPRD 18491316
S710 Phosphorylation HPRD 20068231
S746 Phosphorylation HPRD 19664994
S758 Phosphorylation HPRD 20166139
S763 Phosphorylation HPRD 20166139
Y764 Phosphorylation HPRD 18707149
S767 Phosphorylation HPRD 20166139
T768 Phosphorylation HPRD 18212344
S778 Phosphorylation HPRD 17081983
S790 Phosphorylation HPRD 17081983
Y803 Phosphorylation HPRD 18707149
T805 Phosphorylation HPRD 18669648, 19664994, 19664995
T815 Phosphorylation HPRD 17081983, 20068231
S819 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation HPRD 17016520, 17389395
Y107 Phosphorylation HPRD 17389395
Y112 Phosphorylation HPRD 17016520, 17389395
Y116 Phosphorylation HPRD 17016520, 17389395
Y120 Phosphorylation HPRD 17016520
Y127 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S129 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S131 Phosphorylation HPRD 20166139
S143 Phosphorylation HPRD 18212344
S151 Phosphorylation HPRD 20166139, 18212344
Y156 Phosphorylation HPRD 17016520, 17389395, 18707149
S167 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S168 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y179 Phosphorylation HPRD 17016520, 17389395
S187 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y190 Phosphorylation HPRD 17016520, 18669648, 20068231
Y195 Phosphorylation HPRD 17016520, 20068231
S199 Phosphorylation HPRD 20068231
Y201 Phosphorylation HPRD 20068231
T203 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 17081983
S219 Phosphorylation HPRD 18669648, 20068231
Y220 Phosphorylation HPRD 15951569, 18669648, 20068231
Y233 Phosphorylation HPRD 17016520, 15951569
S245 Phosphorylation HPRD 19664994, 17081983
S248 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S251 Phosphorylation HPRD 20166139, 17081983, 19664995
S568 Phosphorylation HPRD 18491316
T613 Phosphorylation HPRD 18491316
S704 Phosphorylation HPRD 20068231
S740 Phosphorylation HPRD 19664994
S752 Phosphorylation HPRD 20166139
S757 Phosphorylation HPRD 20166139
Y758 Phosphorylation HPRD 18707149
S761 Phosphorylation HPRD 20166139
T762 Phosphorylation HPRD 18212344
S772 Phosphorylation HPRD 17081983
S784 Phosphorylation HPRD 17081983
Y797 Phosphorylation HPRD 18707149
T799 Phosphorylation HPRD 18669648, 19664994, 19664995
T809 Phosphorylation HPRD 17081983, 20068231
S813 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation HPRD 17016520, 17389395
Y107 Phosphorylation HPRD 17389395
Y112 Phosphorylation HPRD 17016520, 17389395
Y116 Phosphorylation HPRD 17016520, 17389395
Y120 Phosphorylation HPRD 17016520
Y127 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S129 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S131 Phosphorylation HPRD 20166139
S143 Phosphorylation HPRD 18212344
S151 Phosphorylation HPRD 20166139, 18212344
Y156 Phosphorylation HPRD 17016520, 17389395, 18707149
S167 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S168 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y179 Phosphorylation HPRD 17016520, 17389395
S187 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y190 Phosphorylation HPRD 17016520, 18669648, 20068231
Y195 Phosphorylation HPRD 17016520, 20068231
S199 Phosphorylation HPRD 20068231
Y201 Phosphorylation HPRD 20068231
T203 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 17081983
S219 Phosphorylation HPRD 18669648, 20068231
Y220 Phosphorylation HPRD 15951569, 18669648, 20068231
Y233 Phosphorylation HPRD 17016520, 15951569
S245 Phosphorylation HPRD 19664994, 17081983
S248 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S251 Phosphorylation HPRD 20166139, 17081983, 19664995
S574 Phosphorylation HPRD 18491316
T619 Phosphorylation HPRD 18491316
S710 Phosphorylation HPRD 20068231
S746 Phosphorylation HPRD 19664994
S758 Phosphorylation HPRD 20166139
S763 Phosphorylation HPRD 20166139
Y764 Phosphorylation HPRD 18707149
S767 Phosphorylation HPRD 20166139
T768 Phosphorylation HPRD 18212344
S778 Phosphorylation HPRD 17081983
S790 Phosphorylation HPRD 17081983
Y803 Phosphorylation HPRD 18707149
T805 Phosphorylation HPRD 18669648, 19664994, 19664995
T815 Phosphorylation HPRD 18669648, 17081983, 20068231
S819 Phosphorylation HPRD 20166139, 18669648, 19664994, ...17081983, 20068231
T831 Phosphorylation HPRD 18669648
T832 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18578522, 20068231
S47 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T59 Phosphorylation HPRD 18212344
Y96 Phosphorylation HPRD 17016520, 15951569
Y174 Phosphorylation HPRD 17016520, 17389395
Y208 Phosphorylation HPRD 17389395
Y213 Phosphorylation HPRD 17016520, 17389395
Y217 Phosphorylation HPRD 17016520, 17389395
Y221 Phosphorylation HPRD 17016520
Y228 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S230 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S232 Phosphorylation HPRD 20166139
S244 Phosphorylation HPRD 18212344
S252 Phosphorylation HPRD 20166139, 18212344
Y257 Phosphorylation HPRD 17016520, 17389395, 18707149
S268 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S269 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y280 Phosphorylation HPRD 17016520, 17389395
S288 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y291 Phosphorylation HPRD 17016520, 18669648, 20068231
Y296 Phosphorylation HPRD 17016520, 20068231
S300 Phosphorylation HPRD 20068231
Y302 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231
T310 Phosphorylation HPRD 17081983
S320 Phosphorylation HPRD 18669648, 20068231
Y321 Phosphorylation HPRD 15951569, 18669648, 20068231
Y334 Phosphorylation HPRD 17016520, 15951569
S346 Phosphorylation HPRD 19664994, 17081983
S349 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S352 Phosphorylation HPRD 20166139, 17081983, 19664995
S669 Phosphorylation HPRD 18491316
T714 Phosphorylation HPRD 18491316
S805 Phosphorylation HPRD 20068231
S841 Phosphorylation HPRD 19664994
S853 Phosphorylation HPRD 20166139
S858 Phosphorylation HPRD 20166139
Y859 Phosphorylation HPRD 18707149
S862 Phosphorylation HPRD 20166139
T863 Phosphorylation HPRD 18212344
S873 Phosphorylation HPRD 17081983
S885 Phosphorylation HPRD 17081983
Y898 Phosphorylation HPRD 18707149
T900 Phosphorylation HPRD 18669648, 19664994, 19664995
T910 Phosphorylation HPRD 17081983, 20068231
S914 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation HPRD 17016520, 17389395
Y107 Phosphorylation HPRD 17389395
Y112 Phosphorylation HPRD 17016520, 17389395
Y116 Phosphorylation HPRD 17016520, 17389395
Y120 Phosphorylation HPRD 17016520
Y127 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S129 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S131 Phosphorylation HPRD 20166139
S143 Phosphorylation HPRD 18212344
S151 Phosphorylation HPRD 20166139, 18212344
Y156 Phosphorylation HPRD 17016520, 17389395, 18707149
S167 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S168 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y179 Phosphorylation HPRD 17016520, 17389395
S187 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y190 Phosphorylation HPRD 17016520, 18669648, 20068231
Y195 Phosphorylation HPRD 17016520, 20068231
S199 Phosphorylation HPRD 20068231
Y201 Phosphorylation HPRD 20068231
T203 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 17081983
S219 Phosphorylation HPRD 18669648, 20068231
Y220 Phosphorylation HPRD 15951569, 18669648, 20068231
Y233 Phosphorylation HPRD 17016520, 15951569
S245 Phosphorylation HPRD 19664994, 17081983
S248 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S251 Phosphorylation HPRD 20166139, 17081983, 19664995
S568 Phosphorylation HPRD 18491316
T613 Phosphorylation HPRD 18491316
S704 Phosphorylation HPRD 20068231
S740 Phosphorylation HPRD 19664994
S752 Phosphorylation HPRD 20166139
S757 Phosphorylation HPRD 20166139
Y758 Phosphorylation HPRD 18707149
S761 Phosphorylation HPRD 20166139
T762 Phosphorylation HPRD 18212344
S772 Phosphorylation HPRD 17081983
S784 Phosphorylation HPRD 17081983
Y797 Phosphorylation HPRD 18707149
T799 Phosphorylation HPRD 18669648, 19664994, 19664995
T809 Phosphorylation HPRD 18669648, 17081983, 20068231
S813 Phosphorylation HPRD 20166139, 18669648, 19664994, ...17081983, 20068231
T825 Phosphorylation HPRD 18669648
T826 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation HPRD 17016520, 17389395
Y107 Phosphorylation HPRD 17389395
Y112 Phosphorylation HPRD 17016520, 17389395
Y116 Phosphorylation HPRD 17016520, 17389395
Y120 Phosphorylation HPRD 17016520
Y127 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S129 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S131 Phosphorylation HPRD 20166139
S143 Phosphorylation HPRD 18212344
S151 Phosphorylation HPRD 20166139, 18212344
Y156 Phosphorylation HPRD 17016520, 17389395, 18707149
S167 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S168 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y179 Phosphorylation HPRD 17016520, 17389395
S187 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y190 Phosphorylation HPRD 17016520, 18669648, 20068231
Y195 Phosphorylation HPRD 17016520, 20068231
S199 Phosphorylation HPRD 20068231
Y201 Phosphorylation HPRD 20068231
T203 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 17081983
S219 Phosphorylation HPRD 18669648, 20068231
Y220 Phosphorylation HPRD 15951569, 18669648, 20068231
Y233 Phosphorylation HPRD 17016520, 15951569
S245 Phosphorylation HPRD 19664994, 17081983
S248 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S251 Phosphorylation HPRD 20166139, 17081983, 19664995
S568 Phosphorylation HPRD 18491316
T613 Phosphorylation HPRD 18491316
S704 Phosphorylation HPRD 20068231
S740 Phosphorylation HPRD 19664994
S752 Phosphorylation HPRD 20166139
S757 Phosphorylation HPRD 20166139
Y758 Phosphorylation HPRD 18707149
S761 Phosphorylation HPRD 20166139
T762 Phosphorylation HPRD 18212344
Y776 Phosphorylation PhosphoSitePlus
T788 Phosphorylation HPRD 17081983, 20068231
S792 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation phospho.ELM 18669648
Y96 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
Y221 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S230 Phosphorylation phospho.ELM 18669648, 18220336
S232 Phosphorylation phospho.ELM 18220336
Y241 Phosphorylation PhosphoSitePlus
S244 Phosphorylation phospho.ELM 18220336
Y248 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
S268 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S269 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
Y280 Phosphorylation PhosphoSitePlus
S288 Phosphorylation phospho.ELM 18669648, 18220336
Y291 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y296 Phosphorylation PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S320 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y321 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S331 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
Y865 Phosphorylation PhosphoSitePlus
T869 Phosphorylation phospho.ELM 18220336
Y904 Phosphorylation PhosphoSitePlus
T906 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T916 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S920 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K930 Ubiquitination PhosphoSitePlus
T933 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y96 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
Y221 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
Y865 Phosphorylation PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
T885 Phosphorylation PhosphoSitePlus
Y941 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18578522, 20068231
S47 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T59 Phosphorylation HPRD 18212344
Y96 Phosphorylation HPRD 17016520, 15951569
Y174 Phosphorylation HPRD 17016520, 17389395
Y208 Phosphorylation HPRD 17389395
Y213 Phosphorylation HPRD 17016520, 17389395
Y217 Phosphorylation HPRD 17016520, 17389395
Y221 Phosphorylation HPRD 17016520
Y228 Phosphorylation HPRD 17016520, 17389395, 17081983, ...20068231
S230 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S232 Phosphorylation HPRD 20166139
S244 Phosphorylation HPRD 18212344
S252 Phosphorylation HPRD 20166139, 18212344
Y257 Phosphorylation HPRD 17016520, 17389395, 18707149
S268 Phosphorylation HPRD 19413330, 18578522, 17081983, ...19664995, 19651622, 18707149, 20166139, 19415658, 18212344
S269 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y280 Phosphorylation HPRD 17016520, 17389395
S288 Phosphorylation HPRD 18669648, 19664994, 19664995, ...18452278
Y291 Phosphorylation HPRD 17016520, 18669648, 20068231
Y296 Phosphorylation HPRD 17016520, 20068231
S300 Phosphorylation HPRD 20068231
Y302 Phosphorylation HPRD 20068231
T304 Phosphorylation HPRD 20068231
T310 Phosphorylation HPRD 17081983
S320 Phosphorylation HPRD 18669648, 20068231
Y321 Phosphorylation HPRD 15951569, 18669648, 20068231
Y334 Phosphorylation HPRD 17016520, 15951569
S346 Phosphorylation HPRD 19664994, 17081983
S349 Phosphorylation HPRD 19413330, 17081983, 19664994, ...20058876, 19664995, 20166139, 20068231
S352 Phosphorylation HPRD 20166139, 17081983, 19664995
S669 Phosphorylation HPRD 18491316
T714 Phosphorylation HPRD 18491316
S805 Phosphorylation HPRD 20068231
S841 Phosphorylation HPRD 19664994
S853 Phosphorylation HPRD 20166139
S858 Phosphorylation HPRD 20166139
Y859 Phosphorylation HPRD 18707149
S862 Phosphorylation HPRD 20166139
T863 Phosphorylation HPRD 18212344
S873 Phosphorylation HPRD 17081983
S885 Phosphorylation HPRD 17081983
Y898 Phosphorylation HPRD 18707149
T900 Phosphorylation HPRD 18669648, 19664994, 19664995
T910 Phosphorylation HPRD 18669648, 17081983, 20068231
S914 Phosphorylation HPRD 20166139, 18669648, 19664994, ...17081983, 20068231
T926 Phosphorylation HPRD 18669648
T927 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18578522, 20068231
S47 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T59 Phosphorylation HPRD 18212344
Y96 Phosphorylation P12931 (SRC) HPRD 17016520, 11382764
Y112 Phosphorylation P12931 (SRC) HPRD 11382764
S122 Phosphorylation HPRD 12885254
Y174 Phosphorylation HPRD 17016520, 17389395, 16212419
Y208 Phosphorylation HPRD 17389395
Y213 Phosphorylation HPRD 17016520, 17389395
Y217 Phosphorylation HPRD 17016520, 17389395, 16212419
Y221 Phosphorylation HPRD 17016520
Y228 Phosphorylation P12931 (SRC) , P00533 (EGFR) HPRD 17016520, 17389395, 14996911, ...20068231
S230 Phosphorylation HPRD 20166139, 18669648, 18212344, ...19664995
S232 Phosphorylation HPRD 20166139
S244 Phosphorylation HPRD 18212344
S252 Phosphorylation P49841 (GSK3B) HPRD 20166139, 12885254, 18212344
Y257 Phosphorylation P12931 (SRC) HPRD 17016520, 17389395, 11382764, ...18707149
S268 Phosphorylation HPRD 19413330, 18578522, 18212344, ...12885254, 19664995, 19651622, 18707149, 20166139, 19415658
S269 Phosphorylation HPRD 19413330, 17081983, 19651622, ...18669648, 20166139, 20068231
Y280 Phosphorylation P12931 (SRC) HPRD 17016520, 17389395, 11382764
S288 Phosphorylation HPRD 18669648, 12885254, 19664994, ...19664995, 18452278
Y291 Phosphorylation P12931 (SRC) HPRD 17016520, 18669648, 11382764, ...20068231
Y296 Phosphorylation P12931 (SRC) HPRD 17016520, 11382764, 20068231
S300 Phosphorylation HPRD 20068231
Y302 Phosphorylation P12931 (SRC) HPRD 11382764, 20068231
T304 Phosphorylation HPRD 20068231
T310 Phosphorylation P49841 (GSK3B) HPRD 12885254
S312 Phosphorylation HPRD 12885254
S320 Phosphorylation HPRD 18669648, 20068231
Y321 Phosphorylation HPRD 15951569, 18669648, 20068231
Y334 Phosphorylation HPRD 17016520, 15951569
S346 Phosphorylation HPRD 19664994, 17081983
S349 Phosphorylation HPRD 19413330, 16083285, 19664994, ...20058876, 19664995, 20166139, 20068231
S352 Phosphorylation HPRD 20166139, 16083285, 19664995
S669 Phosphorylation HPRD 18491316
T714 Phosphorylation HPRD 18491316
S805 Phosphorylation HPRD 20068231
S841 Phosphorylation HPRD 19664994
S853 Phosphorylation HPRD 20166139
S858 Phosphorylation HPRD 20166139
Y859 Phosphorylation HPRD 16212419, 18707149
S862 Phosphorylation HPRD 20166139
T863 Phosphorylation HPRD 18212344
T889 Phosphorylation HPRD 12885254, 20068231
S893 Phosphorylation HPRD 20166139, 19664994, 17081983, ...20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O60716 (CTNND1) S268 P12830 (CDH1) inhibited_association eFIP 21670201
Phosphorylation P33151 (CDH5) Y658 O60716 (CTNND1) increased_association eFIP 24590762
Phosphorylation P33151 (CDH5) Y658 O60716 (CTNND1) decreased_association eFIP 27852896


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 V1 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T27 I27 Biomuta DOID:3571 / liver cancer [ tcga ]
Y96 D96 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
R101 T101 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T147 S147 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S230 I230 Biomuta DOID:3571 / liver cancer [ icgc ]
T235 I235 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R242 S242 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S244 N244 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R249 W249 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ tcga ]
S269 T269 Biomuta DOID:5041 / esophageal cancer [ tcga ]
Y280 C280 Biomuta DOID:1324 / lung cancer [ tcga ]
S312 Y312 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S312 C312 Biomuta DOID:4362 / cervical cancer [ tcga ]
C394 F394 Biomuta DOID:3571 / liver cancer [ icgc ]
K408 E408 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K408 N408 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K444 T444 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K444 * Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S587 P587 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y588 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S617 G617 Biomuta DOID:1324 / lung cancer [ cosmic ]
K622 N622 Biomuta DOID:1612 / breast cancer [ tcga ]
K633 R633 Biomuta DOID:1324 / lung cancer [ tcga ]
T643 I643 Biomuta DOID:1909 / melanoma [ tcga ]
S670 * Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S670 L670 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S675 N675 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:3571 / liver cancer [ tcga ]
S675 T675 Biomuta DOID:1324 / lung cancer [ tcga ]
S713 F713 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T720 A720 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S777 C777 Biomuta DOID:1115 / sarcoma [ tcga ]
K810 T810 Biomuta DOID:363 / uterine cancer [ tcga ]
K878 N878 Biomuta DOID:363 / uterine cancer [ tcga ]
K882 T882 Biomuta DOID:363 / uterine cancer [ tcga ]
T932 I932 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]