Protein Information

Cytoscape View


UniProt AC / UniProt ID O60664 / PLIN3_HUMAN
Protein Name Perilipin-3
Gene Name Name: PLIN3
Synonyms:M6PRBP1,TIP47;
Organism Homo sapiens (Human)

PRO ID PR:O60664
DAG View
PRO Name perilipin-3 (human)
Definition A perilipin-3 that is encoded in the genome of human.
Short Label hPLIN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60664 (PLIN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378, 22223895
S2 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus   UniProt 23186163
S36 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
K65 Acetylation PhosphoSitePlus   UniProt 19608861
K65 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus   UniProt 23186163
S93 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
K122 Sumoylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
S130 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K140 Ubiquitination PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus   UniProt 23186163
T154 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
T170 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S175 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S179 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S187 Phosphorylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus   UniProt 23186163
S217 Phosphorylation PhosphoSitePlus   UniProt 23186163
S241 Phosphorylation PhosphoSitePlus   UniProt 23186163
S243 Phosphorylation PhosphoSitePlus
R245 Methylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 18491316
S11 Phosphorylation HPRD 18491316
T12 Phosphorylation HPRD 18491316
Y95 Phosphorylation HPRD 18707149
S126 Phosphorylation HPRD 18767875, 20068231
S130 Phosphorylation HPRD 19413330, 18767875, 18669648, ...20068231, 18707149
S137 Phosphorylation HPRD 20068231
S160 Phosphorylation HPRD 20068231
T170 Phosphorylation HPRD 18669648
S175 Phosphorylation HPRD 18669648, 20068231
S179 Phosphorylation HPRD 18669648
S187 Phosphorylation HPRD 20068231
S383 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 R11 Biomuta DOID:3571 / liver cancer [ icgc ]
K140 N140 Biomuta DOID:363 / uterine cancer [ tcga ]
S167 F167 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:1909 / melanoma [ icgc, tcga ]
T207 M207 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
T216 K216 Biomuta DOID:3571 / liver cancer [ icgc ]
K289 N289 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
S303 R303 Biomuta DOID:1115 / sarcoma [ tcga ]
K356 N356 Biomuta DOID:363 / uterine cancer [ tcga ]
T415 M415 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K428 E428 Biomuta DOID:3070 / malignant glioma [ cosmic ]