Protein Information

Cytoscape View

UniProt AC / UniProt ID O43699 / SIGL6_HUMAN
Protein Name Sialic acid-binding Ig-like lectin 6 precursor
Gene Name Name: SIGLEC6
Organism Homo sapiens (Human)

PRO ID PR:O43699
DAG View
PRO Name sialic acid-binding Ig-like lectin 6 (human)
Definition A sialic acid-binding Ig-like lectin 6 that is encoded in the genome of human.
Short Label hSIGLEC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O43699 (SIGLEC6) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N103 N-Glycosylation GlyGen 24190977
S107 Phosphorylation PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
N233 N-Glycosylation GlyGen 24190977
N258 N-Glycosylation GlyGen 24190977
Y426 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S107 N107 Biomuta DOID:1909 / melanoma [ cosmic ]
K136 N136 Biomuta DOID:363 / uterine cancer [ tcga ]
Y426 C426 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]