Protein Information

Cytoscape View


UniProt AC / UniProt ID O43684 / BUB3_HUMAN
Protein Name Mitotic checkpoint protein BUB3
Gene Name Name: BUB3
Organism Homo sapiens (Human)

PRO ID PR:O43684
DAG View
PRO Name mitotic checkpoint protein BUB3 (human)
Definition A mitotic checkpoint protein BUB3 that is encoded in the genome of human.
Short Label hBUB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43684 (BUB3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Sumoylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S18 Phosphorylation PR:O43683 (hBUB1) PRO 20057499
S19 Phosphorylation O43683 (BUB1) PhosphoSitePlus 20057499
K21 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
R126 Methylation PhosphoSitePlus
T127 Phosphorylation PhosphoSitePlus
C129 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
K139 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
R149 Methylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K179 Acetylation PhosphoSitePlus   UniProt 19608861
K179 Ubiquitination PhosphoSitePlus
R186 Methylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation P14618 (PKM) PhosphoSitePlus   RLIMS-P 24316223
S211 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 15302935, ...23186163
K216 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K322 Acetylation PhosphoSitePlus
K322 Sumoylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S325 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
C327 S-Nitrosylation dbSNO 26338901
T328 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T154 Phosphorylation HPRD 20068230
Y194 Phosphorylation HPRD 17322306
S211 Phosphorylation HPRD 18669648, 15302935, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T154 Phosphorylation HPRD 20068230
Y194 Phosphorylation HPRD 17322306
S211 Phosphorylation HPRD 18669648, 15302935, 18452278


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000035437 (hBUB3/Phos:1) pS18 PR:O43683 (hBUB1) PRO 20057499


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O43683 (hBUB1) Interaction PR:O43684 (hBUB3) PRO 10198256, 15525512
PR:O43684 (hBUB3) Interaction PR:P25054 (hAPC) PRO
PR:O43684 (hBUB3) Interaction PR:O15350-5 (hTP73/iso:5) PRO 20057499
PR:O43684 (hBUB3) Interaction PR:O60566 (hBUB1B) PRO 17785528
PR:O43684 (hBUB3) Interaction PR:Q12834 (hCDC20) PRO
PR:O43684 (hBUB3) Interaction PR:O15350-3 (hTP73/iso:3) PRO 20057499
PR:O43684 (hBUB3) Interaction PR:Q9Y6D9 (hMAD1L1) PRO 10198256
PR:O43684 (hBUB3) Interaction PR:Q13257 (hMAD2L1) PRO
PR:O43684 (hBUB3) Interaction PR:O15350-1 (hTP73/iso:1) PRO 20057499
PR:O43684 (hBUB3) Interaction PR:O15350-2 (hTP73/iso:2) PRO 20057499
PR:O43684 (hBUB3) Interaction PR:O43683 (hBUB1) PRO 10198256
PR:O60566 (hBUB1B) Interaction PR:O43684 (hBUB3) PRO 20016069
PR:P25054 (hAPC) Interaction PR:O43684 (hBUB3) PRO 11283619
PR:Q13257 (hMAD2L1) Interaction PR:O43684 (hBUB3) PRO
PR:Q9Y6D9 (hMAD1L1) Interaction PR:O43684 (hBUB3) PRO 10198256