Protein Information

Cytoscape View


UniProt AC / UniProt ID O43474 / KLF4_HUMAN
Protein Name Krueppel-like factor 4
Gene Name Name: KLF4
Synonyms:EZF,GKLF;
Organism Homo sapiens (Human)

PRO ID PR:O43474
DAG View
PRO Name krueppel-like factor 4 (human)
Definition A krueppel-like factor 4 that is encoded in the genome of human.
Short Label hKLF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43474 (KLF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus   UniProt 18655026
S132 Phosphorylation RLIMS-P 29526737
S234 Phosphorylation PhosphoSitePlus   RLIMS-P 31281496
S236 Phosphorylation PhosphoSitePlus
S240 Phosphorylation phospho.ELM 18220336
S244 Phosphorylation PhosphoSitePlus
S251 O-Glycosylation GlyGen 29237092
S254 Phosphorylation PhosphoSitePlus   UniProt 20068231
S258 Phosphorylation PhosphoSitePlus
K278 Sumoylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
T429 Phosphorylation RLIMS-P 25116380
S444 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
K448 Sumoylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S236 Phosphorylation HPRD 20068231
S244 Phosphorylation HPRD 20068231
S254 Phosphorylation HPRD 18669648, 20068231
T316 Phosphorylation HPRD 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O43474 (KLF4) S132 O14980 (XPO1) inhibited_association eFIP 29526737
Phosphorylation P40763 (STAT3) Y705 O43474 (KLF4) unknown eFIP 24129709
Phosphorylation Q92769 (HDAC2) S424 O43474 (KLF4) inhibited_association eFIP 19486889