Protein Information

Cytoscape View


UniProt AC / UniProt ID O15460 / P4HA2_HUMAN
Protein Name Prolyl 4-hydroxylase subunit alpha-2 precursor
Gene Name Name: P4HA2
ORFNames:UNQ290/PRO330;
Organism Homo sapiens (Human)

PRO ID PR:O15460
DAG View
PRO Name prolyl 4-hydroxylase subunit alpha-2 (human)
Definition A prolyl 4-hydroxylase subunit alpha-2 that is encoded in the genome of human.
Short Label hP4HA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15460 (P4HA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
N264 N-Glycosylation GlyGen 24190977
T272 O-Glycosylation GlyGen 30459171
K300 Ubiquitination PhosphoSitePlus
K328 Sumoylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
Y421 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
Y487 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K443 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T31 N31 Biomuta DOID:3571 / liver cancer [ icgc ]
T447 M447 Biomuta DOID:4362 / cervical cancer [ tcga ]
Y487 * Biomuta DOID:3571 / liver cancer [ icgc ]