Protein Information

Cytoscape View


UniProt AC / UniProt ID O15372 / EIF3H_HUMAN
Protein Name Eukaryotic translation initiation factor 3 subunit H
Gene Name Name: EIF3H
Synonyms:EIF3S3;
Organism Homo sapiens (Human)

PRO ID PR:O15372
DAG View
PRO Name eukaryotic translation initiation factor 3 subunit H (human)
Definition A eukaryotic translation initiation factor 3 subunit H that is encoded in the genome of human.
Short Label hEIF3H
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15372 (EIF3H) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   UniProt 23186163
K5 Ubiquitination PhosphoSitePlus
T8 Phosphorylation HPRD   PhosphoSitePlus 17924679
S10 Phosphorylation HPRD   PhosphoSitePlus 17924679
T11 Phosphorylation HPRD   PhosphoSitePlus 17924679
S15 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
K24 Acetylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
S31 Phosphorylation HPRD   PhosphoSitePlus 20068230
K37 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S183 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 23186163, 17081983, ...18767875, 19651622, 17322306, 20068231, 18544531, 17322308
K188 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
K274 Acetylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 P3 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ]
S3 F3 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K26 R26 Biomuta DOID:363 / uterine cancer [ tcga ]
K178 R178 Biomuta DOID:1324 / lung cancer [ tcga ]
K180 N180 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K220 T220 Biomuta DOID:363 / uterine cancer [ tcga ]
K220 N220 Biomuta DOID:363 / uterine cancer [ tcga ]
K241 T241 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S316 L316 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:1324 / lung cancer [ cosmic ]
S316 P316 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K340 N340 Biomuta DOID:1909 / melanoma [ cosmic ]